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  • Meet Dr. Jung-min Bae, "the Master of Vitiligo Treatment”

    [Prof. Huh’s Talk on Dermatologic Medical Devices] LaserOptek ③Voice from the Field (Fin) Prof. Chang Hun Huh, at the department of dermatology of Seoul National University Bundang Hospital, visited Dr. Jung-min Bae of the Heal House Skin Clinic, who is expertly treating many vitiligo patients with LaserOptek's Pallas laser. (Prof. Huh on the left and Dr. Bae on the right.) When I started this column, I've decided to write it on the site, not on the desk. Prof. Jung-min Bae, who appeared like a rising star in dermatologic journals in recent years, told me that he had left university hospital and opened a private clinic. "Heal House Skin Clinic" was the name of it and its meaning is "a healing house for patients." He has been globally known as an expert in treating vitiligo with Pallas laser. I interviewed him in person and listened to his story. - Why did you suddenly open a private clinic and left a university hospital, where is easy to conduct numerous researches? It is because I wanted to encounter more vitiligo patients, closely. I’ve accumulated clinical and research experiences on vitiligo treatment at a university hospital. Being able to conduct various research was a great benefit of working at a university hospital, but there were some cons. I always felt inconvenience for not seeing more patients due to limited consultation hours. Also, focusing on vitiligo, my area of expertise, was not easy because of the many general dermatologic patients. That’s why I decided to open a vitiligo specialized clinic based on my experience so far. I developed a “vitiligo total care center” with Pallas laser which can treat vitiligo effectively, admission and operating rooms for surgical procedures, vitiligo special nurses, and special skincare programs for vitiligo. Dr. Bae who is well known as "the master of vitiligo treatment” has recently opened a private clinic focusing on treating vitiligo, while communicating with a lot more patients and providing safe and effective treatments. - What is the most effective vitiligo treatment? The basic treatments for vitiligo are NBUVB and Pallas laser. Especially, Pallas laser has a much more beneficial to small size or facial lesion because it can skip the irradiation of UV rays on the normal skin. - Is there any pain or side effect when using the laser on sensitive areas of skin like around the eyes? Generally, there are no pain or side effects serious enough to stop the treatment. Wavelengths of Pallas laser do not penetrate through whole layers of skin. Also, you don’t have to worry about it since when you close your eyes, the pupils move upward and be covered safely under the frontal bone. Even if the laser is accidentally irradiated on the eyes, there might be temporal damage to cornea or lens, but no permanent damage to the retina or optic nerves has been reported. As preventing accidents is essential, I am putting every effort into safety when doing laser procedures. Alopecia totalis treated by Pallas laser. A: Before, B: After 3 months, C: After 7 months (photos from Laser in Medical Science 2020;35:999-1002) - Are there any differences in the effects of Pallas laser treatment by age groups? It is more effective if the patient is younger. Pallas laser can be used safer and easier even on patients with claustrophobia or children who cannot use cabinet type UV treatment devices. Besides, it is a safe and effective treatment for not only children and elderly but also even pregnant women. - What are treatment cycles and post-treatment care? In general, 2 sessions per week are basic, but it might be adjustable 1~3/week according to the cases. Pallas laser treatment does not have any downtime, so patients can return to daily life right after the procedure. However, UV exposure should be avoided. - What other diseases can be treated with Pallas laser? Pallas has already been in use for vitiligo and psoriasis. Also, it seems to be highly effective in atopic dermatitis and alopecia areata in my personal experience so far. Indeed, Pallas laser treatment has no pain at all, so it is expected to be the new hope for the pediatric alopecia areata patient who is not easy to get injected due to pain. - What are the differences between Pallas laser and previous Excimer lasers? A wavelength of the classic Excimer laser is 308nm, and that of Pallas laser is 311nm. The difference between wavelengths is minimal, but the biologic difference is not small. According to the previous research data conducted at the university hospital, minimal erythema dose of Pallas laser was 1.7 times higher and penetrated deeper than Excimer, resulting in greater treatment effects. Tag#PallasLaser#Laseroptek http://www.k-health.com

    2020.08.01

  • Picosecond Fractional Lasers, Proved Benefits on Treating Acne Scars

    Picosecond Fractional Lasers, Proved Benefits on Treating Acne Scars Pockmarks created from acne bring pigmentations and widened pores, becoming a stress factor of patients. Until now, general fractional lasers had been used for treating pockmarks, but the March issue of Dermatologic Therapy reported that Korean physicians have discovered that picosecond fractional laser with 1064nm of wavelengths can effectively treat pockmarks. The clinical trial was operated by using the DOE fractional beam of LaserOptek’s PicoLo laser to patients with pockmarks caused by pimples. After the patients had received more than three times of treatments with one month of intervals, they showed satisfaction and minimal pain. Three months later, specialists confirmed more than 58% of the effects in their objective evaluations. Photo= Dermatologic Therapy. 2020;e13297. Photos of before and after the treatment. Biopsy conducted after irradiating the laser confirmed the superficial cystic cavitation in the tissue, and it was found that this tissue reaction was observed only in picosecond lasers using ultra-short waves, which resulted in therapeutic effects. "Because pigment lasers are irradiated fractionally, the scars improved along with brightening of overall face color and increase in collagen production, which can give a sense of skin tightening," Dr. Seung Hwan Paik from the Seoul One Dermatology, who led the clinical trial while working in Asan Medical Clinic, commented. http://www.k-health.com

    2020.07.16

  • Ti:sapphire Laser “Pallas,” Side Effects↓ Benefits↑

    Applicable for psoriasis, vitiligo, atopic dermatitis, alopecia areata, etc. [Prof. Huh’s Talk on Dermatologic Medical Devices] LaserOptek ② Phototherapy Lasers In ancient Egypt and India, treating skin diseases with materials found in nature was tried even though there were no accurate treatments. These methods had passed on via Ebers Papyrus, and some parts were reinterpreted and are being used today. Light has been used to treat skin diseases 3,500 years ago. Vitiligo has been treated by sunbathing with eating certain plant extracts or seeds and psoralen, a photosensitizer (light-sensitive compound), is isolated later and used as a main phototherapy remedy today. Modern phototherapy had been advanced by Niels Finsen, who used phototherapy for scrofuloderma and won the Nobel Prize in 1903. Then phototherapies with tar by William Goeckerman, anthralin by John Ingram, and psoralen (PUVA) have been applied. Diseases proved efficacies of phototherapy are vitiligo (skin became white because of the local pigment loss), psoriasis (characterized by hyperkeratosis and scales due to abnormal multiplication of skin cells), cutaneous T cell lymphoma, atopic dermatitis, alopecia areata, etc. After Parrish and Jaenicke discovered that 313nm wavelengths are the best for treating psoriasis, the narrowband UVB, which uses the wavelengths of 311-313nm, has begun to be standard phototherapy. Phototherapy is beneficial to various skin diseases; however, long-term irradiation of UV rays increases the possibility of skin cancer and photoaging. To minimize these problems, irradiation of narrowband UV rays on the only affected lesion is ideal, but routine phototherapy irradiates all parts of the skin within a certain area, thus those adverse effects are hard to avoid. Hence, irradiating a strong light only on the affected lesion is the ideal phototherapy, and the best tool for this is a laser. The first laser used for these purposes was an excimer laser, which emits 308nm wavelengths of xenon gas and treated many patients with psoriasis and vitiligo. But, a problem of its maintenance cost because of the gas used, and the wavelengths are a little shorter than 311nm—the best wavelength for the treatment—were often pointed out from excimer laser. LaserOptek is reporting many clinical effects by inventing the world’s first “Pallas,” a laser device that is closer to existing UV rays therapy theory, and maintenance cost is much less as a solid-state. Pallas is a titanium sapphire laser, creating 933nm wavelengths of laser beams but reduce 1/3 of its wavelength by third-harmonic generation technology. 311nm wavelengths are not only even closer to the 313nm wavelengths, which are well known as the most effective wavelengths on psoriasis, but also it can penetrate deep into the skin. Moreover, Pallas has 1.7 times more minimal erythema doses (MED) than other lasers, and that it can irradiate stronger with more benefits and fewer side effects. Just like conventional NBUVB treatments, indications of this laser include various autoimmune diseases such as psoriasis, vitiligo, atopic dermatitis, and alopecia areata. These clinical effects have been reported on leading SCI journals such as the Journal of the American Academy of Dermatology, Lasers in Medical Science, JAMA Dermatology, Photodermatology, Photoimmunology & Photomedicine, and others. https://www.k-health.com/news/articleView.html?idxno=49188

    2020.07.07

  • LaserOptek Presents Innovative Medical Devices Created by Professional Laser Engineers

    Key technologies of Laseroptek: laser resonators, short-pulse laser, harmonic generation, regenerative amplifier, and power supply An export-focused company that strives to broaden oversea markets [Prof. Huh’s Talk on Dermatologic Medical Devices] LaserOptek ① Company Exploration So-called “Homo Hundred” era, the skin beauty market gained momentum as the social atmosphere has turned to pursue a healthy, vibrant life. Particularly, dermatologic medical devices have made remarkable progress by expanding into various areas including diagnosis and treatment. Health Kyung Hyang would like to start to explore the evolved dermatologic medical devices through a column titled “Prof. Huh’s Talk on Dermatologic Medical Devices.” Prof. Chang-Hun Huh is a professor at the dermatologic department of Seoul National University Bundang Hospital, and he visited related sites to get a better quality of data, wishing for further development of the Korean dermatologic medical device industry. Readers can see the present and future of the medical skin device industry through more vivid and meaningful information achieved from on-site.<editor's note=> Last May 16 was the 60th anniversary of the world’s first laser invention by the genius scientist named “Theodore Maiman” in California. Lasers look like a deadly murder weapon in science fiction movies, but they are essential equipment in real life like a barcode scanner and a CD player. In the medical field, especially in the dermatologic field, we can’t address medical devices without mentioning lasers. █ LaserOptek = Hong Chu, a founder and chairman, had been a professor teaching about laser optics in KIST (Korea Institute of Science and Technology). With a start-up foster policy for professors by the government, he founded the company in 2000 to make the best laser system with Korean technologies. The company name "LaserOptek" stands for "laser optics technology." They developed a laser system with their technology shortly after the company’s establishment. In the beginning, they also developed industrial lasers in parallel, but now they pay more attention to the research, development, and manufacturing of medical lasers. At the background of the advanced technology, there was a firm research team led by Sang Hyuk Kim, Ph.D. (Chief of R&D center) and Aleksandr Tarasov, Ph.D. (Principal Research Scientist) who were former researchers at KIST. With great efforts of these two men, LaserOptek can get numerous patents and be able to design their own core parts including a laser resonator. In 2019, they also won “the Korea Technology Award” by “the Minister of Trade, Industry, and Energy” for the first time in the beauty laser field with “An ultra-fast switching laser-based treatment system with variable wavelength.” Since 2018, Mr. Chang Jin Lee, MBA, has been joined as a president to support marketing, which was relatively weak compared to its high technology and good reputation and to make it stand as a global laser company. With his help, LaserOptek could achieve more certifications of the oversea market and over 30% increment in annual sales. █ Product Line = There are four major product lines and they produce all core parts by themselves: Q-switched Nd:YAG product line of nanoseconds or picoseconds for pigment diseases (Helios, PicoLo), Solid-state UV laser line for vitiligo or psoriasis(Pallas), Er:YAG laser line for peeling or tissue removal (Lotus), and long-pulsed laser line for hair removal, vascular lesion, et al. (Hyperion, Zelos). Their key technologies are ▲Design of laser resonators (gas, liquid, solid) ▲Short-pulse laser design (Q-switch, mode-locking, pulse compression) ▲Harmonic generation design ▲Regenerative amplifier design ▲Power supply design. With these technologies, the company could secure developing new lasers, maintaining high stability, and improving beam quality. █ Challenges = Exports account for more than 70% in LaserOptek. Currently. The main export countries were Asian countries including Taiwan and Southeast Asia, but exports to the United States, Europe (Turkey, Belgium, the Netherlands, Switzerland, etc.), and the Middle East have begun since last year. The most difficult challenges in exploring overseas markets are ▲lack of local information ▲time and cost to get and maintain certifications of each country ▲excessive competition within Korean companies in Southeast Asia ▲establishment of brand values in North America and Europe ▲service problems in remote areas, etc. Besides, medical devices, especially beauty medical devices, have a short trend cycle and that a new device should timely come out in the market, but it is not easy due to the long period for certification in Korea. Because a large-scale clinical trial is not available before getting approval for sales, there is a slight lack of time for market development, too. It will be a great help to an export-oriented company like LaserOptek if the government pays more attention and deregulate macroscopically in the future. █ Future Plans = Although it is one of the top three laser companies in Korea in terms of sales, currently, they set goals to develop 2~3 innovative products annually with their own leading technology and to become one of the Big 5 global laser companies within next five years. Recently, they succeeded in getting 10 billion KRW investment. With this, they will enforce research capabilities to develop and release on the market with various product lines. They also have a plan to strengthen marketing and branding as well as continuous R&D investment. If the plan is successfully carried out, it is likely that products of LaserOptek, a Korean laser company, will replace the foreign laser devices in Korea. https://www.k-health.com/news/articleView.html?idxno=48828

    2020.06.09

  • PicoLO received CE approval ⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀

    PicoLO received CE approval -Picosecond Nd:YAG laser(1064&532nm) -Gold Standard for Tattoo Removal -High STability for Optimal Results ⠀

    2020.03.04